Early Bubble Continuous Positive Airway Pressure Therapy for Premature Neonates with Respiratory Distress Syndrome

Objective: To determine the outcome of preterm neonates with early introduction bubble continuous positive airway pressure (CPAP). Methodology: This observational study was conducted in NICU Shifa International Hospital, Islamabad from March 2017 to August 2017. Ninety infants were enrolled a gestational age 28 37 weeks and clinical features Respiratory Distress Syndrome (RDS). Infant variables that recorded birth weight, age, severity RDS Fio2 requirement. Bubble CPAP started at 5cm water FiO2 adjusted maintain SpO2 87 95%. The SPSS 26 version used analyze data. Chi square test used, P value <0.05 considered significant. Results: included 90 who clinically diagnosed RDS. treat RDS, mean 5.27 hours life standard deviation 2.66 hours. 11 out (11.22%) babies had chest X-ray findings favor severe RDS; while X-rays remaining 79 (88.78%) showed mild moderate Conclusion: is valuable importance low resource countries lack ventilators provides an adequate conservative treatment method for neonates. However, cases intubation mechanical ventilation are often necessary.